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920-106 exam Dumps Source : NNCSS SYMPOSIUM convoke CENTER

Test Code : 920-106
Test denomination : NNCSS SYMPOSIUM convoke CENTER
Vendor denomination : Nortel
braindumps : 90 true Questions

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VoIP certification tracks - Nortel's support certifications | true Questions and Pass4sure dumps

As outlined in a outdated tip, companies are implementing IP telephony more commonly on their facts infrastructures. The accelerated deployment has created a necessity for certified IP telephony engineers to deliver proven, most beneficial-of-breed expertise.

The IP telephony certifications Nortel at present presents are divided into four classes: lead specialist, Design expert, support skilled, and Design skilled. This tip discusses the Nortel support music.

assist specialist

The lead professional certifications are intended to demonstrate an individual's means to deliver into effect, operate, and troubleshoot a Nortel Networks IP Telephony answer. The support expert certification reflects a candidate with three to six months of event that can deal with pursuits technical issues of a common Nortel IP Telephony answer.

NNCSS - VoIP Succession BCM 3.0

This certification checks the skill to deliver into effect, function, and troubleshoot the company Communications supervisor three.0. This certification covers hardware, beginning-up, facts and voice networking, applications, and troubleshooting the BCM. To stream the certification, two checks necessity to breathe successfully completed: know-how requisites and Protocols for IP Telephony options, and Succession BCM three.0. The technology necessities and Protocols for IP Telephony solutions exam is an silhouette of convergence technologies.

NNCSS - CallPilot Rls. 2.0

This certification exams the means to deliver in force, function, and troubleshoot the VoIP CallPilot 2.0. This certification covers hardware, administration, interoperability with Meridian 1 switches, and security of a lone website CallPilot system. To stream the certification, two tests must breathe successfully achieved: Meridian Database and CallPilot 2.0.

NNCSS - Symposium denomination middle Server or Symposium denomination focus Server installation and protection

These two certifications peer at various the skill to implement, operate, and troubleshoot the Symposium denomination focus Server. both certifications cover hardware, utility installing, administration, and protection of Symposium convoke core Server 4.2, Symposium web client 4.0, and Symposium categorical three.0. besides the fact that children, the Symposium convoke focus Server certification likewise tests the architecture, customized configuration and integration of the server. To pass either of those certifications, one exam contain to breathe efficiently achieved: Symposium convoke focus or Symposium convoke core installation and maintenance, respectively.

NNCSS - Symposium convoke focus TAPI/Agent or convoke focus TAPI/Agent installing and preservation

These two certifications verify the skill to deliver in force, operate, and troubleshoot the Symposium denomination focus TAPI/Agent. each certifications cover hardware, software setting up, administration, and renovation of Symposium TAPI 2.three and Symposium Agent 2.three. however, the Symposium convoke focus TAPI/Agent certification likewise checks the structure, integration, and custom configuration of the TAPI/Agent. To lag both of those certifications, one examination must breathe efficaciously completed: Symposium convoke middle TAPI/Agent or Symposium convoke core TAPI/Agent Inst/leading, respectively.

NNCSS - Symposium specific convoke core or Symposium express denomination middle installation and renovation

These certifications examine the skill to enforce, function, and troubleshoot the Symposium specific denomination middle. both certifications cowl hardware, utility installing, administration, and protection of Symposium express convoke focus four.2. despite the fact, the Symposium categorical convoke focus certification likewise checks the structure and integration of the denomination middle. To stream both of the certifications, one examination ought to breathe efficiently accomplished: Symposium categorical convoke focus or Symposium categorical convoke focus Inst and Maint respectively.

NNCSS - VoIP Multimedia communique Server (MCS) 5100 2.0

This certification tests the capability to implement, operate, and troubleshoot the VoIP Multimedia verbal exchange Server (MCS) 5100 2.0. This certification covers setting up of the hardware and application, configuration, preservation, and administration of the Multimedia communication Server (MCS) 5100 2.0. To lag the certification, two assessments must breathe efficiently achieved: expertise standards and Protocols for IP Telephony solutions, and VoIP Multimedia verbal exchange Server (MCS) 5100 2.0. The know-how specifications and Protocols for IP Telephony options examination is an overview of convergence technologies.

NNCSS - VoIP Succession 1000/1000M Rls. 3.0 DB Administrator

This certification checks the potential to preserve and troubleshoot the VoIP Succession 1000/1000M Rls. three.0 DB Administrator. This certification covers the structure, configuration, upkeep, and administration of the Meridian 1, Succession one thousand Rls. 3.0, and Succession 1000M Rls. 3.0 the consume of simple Alternate Route alternative (BARS) and network Alternate Route selection (NARS). To circulate the certification, two tests necessity to breathe successfully completed: expertise requisites and Protocols for IP Telephony solutions, and Succession a thousand/1000M Rls. 3.0 DB Administrator.

NNCSS - VoIP Succession one thousand/1000M Rls. three.0 setting up and upkeep

This certification exams the capacity to set up, configure, and maintain the VoIP Succession 1000/1000M Rls. 3.0. This certification covers the setting up, structure, configuration, preservation, and administration of the Meridian 1, Succession one thousand Rls. 3.0, and Succession 1000M Rls. three.0, cyber web Telephones i2xxx, and Optivity Telephony manager (OTM) 2.1. To circulate the certification, three tests must breathe efficaciously achieved: know-how specifications and Protocols for IP Telephony solutions, and Succession 1000/1000M Rls. 3.0 for Technicians, and Succession 1000/1000M Rls. three.0.

support professional

The aid expert certifications build on the specialist's expertise by demonstrating their skill to deliver in force, operate, and troubleshoot an advanced Nortel Networks IP Telephony solution. The succor professional certifications reflect a candidate with six to twelve months of fingers-on journey with the means to lead or aid intermediate-level personnel to preserve complex Nortel IP Telephony solutions.

NNCSE - CallPilot 2.0 Unified Messaging options

This certification assessments the skill to enforce, operate, troubleshoot and optimize the VoIP CallPilot Unified Messaging solution 2.0. This certification covers the installing, administration, interoperability, security, ameliorate techniques and feature usage for a multi web site CallPilot system. To pass the certification, the candidate necessity to first gain their NNCSS - CallPilot Rls. 2.0. consequently, the CallPilot 2.0 Unified Messaging solutions contain to breathe efficaciously completed to acquire this certification.

NNCSE - Contact middle

This certification checks the potential to deliver into effect, operate, troubleshoot and optimize the Contact focus products. This certification covers the candidate's capabilities on the Symposium convoke middle Server (SCCS)/Symposium express convoke middle/Symposium net customer, Symposium TAPI service provider (TAPI SP), Symposium Agent, and the Symposium net focus Portal. To circulate the certification, the candidate ought to first acquire their NNCSS - Symposium denomination focus Server and the NNCSS - Symposium convoke focus TAPI/Agent certification. in consequence, the Contact middle examination contain to breathe correctly accomplished to garner this certification.

NNCSE - IP Convergence Succession 1000/1000M Rls. 3.0

This certification checks the means to deploy, configure, retain, and optimize the VoIP Succession 1000/1000M Rls. 3.0. This certification covers the configuration, succession department office (BO), remote workplace, operation, and Meridian 1 to Succession 1000M three.0 migration procedures for the Succession a thousand/1000M Rls. 3.0, web Telephones i2xxx, faraway office 91xx, and Optivity Telephony manager (OTM) 2.1. To pass the certification, the candidate contain to first obtain their NNCSS - VoIP Succession CSE 1000 Rls. 2.0 or the VoIP Succession 1000/1000M Rls. 3.0 installing & maintenance certification. as a result, an extra greater problematic version of the Succession 1000/1000M Rls. three.0 examination should breathe efficaciously achieved to achieve this certification.

within the IT trade, certifications are a system to validate an individual's edge within a exact area. The above Nortel IP Telephony certifications are probably the most paraphernalia that may pomp the capabilities of an IP Telephony assist professional. These certifications couldn't substitute years of industry event, however they enact deliver the foundation to support and maneuver Nortel Voice over IP solutions.

The next tip will talk about Nortel's Design IP Telephony certification music.

Richard Parsons (CCIE#5719) is a manager of skilled capabilities for Callisma Inc., a totally owned subsidiary of SBC. He has constructed a superb groundwork in networking ideas, advanced troubleshooting, and monitoring in areas akin to optical, ATM, VoIP, routed, routing, and storage infrastructures. wealthy resides in Atlanta GA, and is a graduate of Clemson institution. His legacy includes senior and predominant consulting positions at international network features, Lucent, and Callisma.

Bel Fuse (BELFB) this plunge 2018 revenue conference convoke Transcript | true Questions and Pass4sure dumps

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Bel Fuse (NASDAQ:BELFB)this autumn 2018 earnings convention CallFeb. 21, 2019 11:00 a.m. ET

  • organized Remarks
  • Questions and solutions
  • name participants
  • organized Remarks:


    first rate day, and welcome to the Bel Fuse Inc. fourth quarter and full-year 2018 results conference name. modern day convention is being recorded. at present, i want to account for the convention over to Mr.

    Dan Bernstein, president and chief executive officer. please proceed ahead, sir.

    Dan Bernstein -- President and Chief govt Officer

    thank you, Allison. becoming a member of me on the denomination nowadays is Craig Brosious, their vice president of Finance; and Lynn Hutkin, their director of fiscal reporting. earlier than they start the call, i might fancy to request Lynn to lag over the secure harbor remark. Lynn?

    Lynn Hutkin -- Director of fiscal Reporting

    thank you, Dan. decent morning, everybody. before they start, i might fancy to read here secure harbor statement. except for historic suggestions contained on this call, the concerns discussed on this denomination corresponding to statements related to expected enlarge from the business's distribution channel, the results of the ERP system implementation and different high-quality commerce and enlarge traits are forward-searching statements as described below the inner most Securities Litigation Reform Act of 1995 that involves dangers and uncertainties.

    exact effects could fluctuate materially from those projections. among the factors that might trigger genuine consequences to vary materially from such statements are: the market considerations facing their purchasers; the continuing viability of sectors that weigh on their products; the outcomes of company and economic conditions; difficulties associated with integrating currently obtained agencies; means and supply constraints or difficulties; product building, commercialization or technological difficulties; the regulatory trade ambiance; dangers associated with foreign currency; uncertainties associated with prison proceedings; the market's acceptance of the business's modern items and competitive responses to these modern products; the influence of alterations to U.S. change and tariff policies; and the risk elements exact sometimes within the company's SEC stories. In simple of the hazards and uncertainties, there may likewise breathe no assurance that any forward-looking statement will, in fact, account for to breathe proper.

    We undertake no duty to update or revise any ahead-looking statements. They may additionally likewise talk about non-GAAP effects throughout this convoke and reconciliations of their GAAP consequences to non-GAAP effects were protected in their liberate. And simply earlier than turning the denomination back to Dan, I simply desired to supply each person a heads up that their EBITDA reconciliation table in their customary release became fallacious. there were errors in that desk and a brand modern release is popping out.

    So please sack that preliminary desk. So it truly is the third table, which is on web page 7 of the liberate.

    Dan Bernstein -- President and Chief govt Officer

    thanks, Lynn. earlier than going throughout the financials, i want to provide a short update on how the companies did from an operational standpoint this quarter and what they descry going ahead. usual, we're very completely satisfied that they closed the 12 months with a different tenacious quarter, bringing their 2018 sales to $548 million, their larger revenue year for the intuition that 2015. extra importantly, their net income for the year of $21 million become the highest in over a decade.

    revenue bar nonexistent the route through the fourth quarter were $142.7 million, up 19% from the fourth quarter of 2017 with double-digit growth in each and every of the 3 leading product lines. Their backlog of orders remained mighty at $171.2 million at December 31, 2018, a mount of 17% from a 12 months in the past. The enhance in backlog is likewise considered across every of their main product companies, which is a favorable barometer for different future increase. and searching via at the replete 12 months.

    Our Magnetic solutions neighborhood closed the 12 months with $24.4 million enhance in sales over 2017 stages led by tall exact for their built-in connector modules that are used in next-technology switching functions. revenue of their signal Transformer items contain been additionally potent prerogative through 2018 as modern courses with clinical and industrial purposes moved into replete production. they now contain likewise increased the presence of their magnetic items via their distribution channels, which add to the 12 months-over-12 months sales growth. The backlog of orders from magnetic items grew by route of $9.7 million or 28% enhance for the intuition that the 2017 yr-end.

    Our Connectivity solutions neighborhood had yr-over-year revenue enlarge of $sixteen.four million. Their Cinch enterprise expanded profits via $8.2 million compared to 2017 led via mighty exact for optical and copper products utilized in encryption, communication and threat detection radar applications. Their Stewart passive connectors additionally saw boost in income of $8.2 million from 2017 as better pecuniary conditions in the pile commerce led to tall exact for their premise wiring customs throughout the year. The Cinch and Stewart enterprise likewise benefit from wonderful enlarge in earnings through their distribution channel in 2018.

    average, the backlog of orders for their Connectivity products grew by using $7.8 million, or 16%, in view that 2017 12 months-conclusion stages. Their power options and insurance policy community had a turnaround yr as revenue boom of $15.8 million from 2017 led this community to its first 12 months of sales enlarge when you respect that 2015. with the exception of the consequences of their NPS divestiture, sales for this group were up $21 million or 14% from closing 12 months, pushed by route of continued exact for their power supplies in diversity of information core functions. sales of their DC to DC and circuit insurance policy products likewise grew in 2018, offset by using a decline favorite for their custom modules.

    The backlog of their orders for their vigour solutions and insurance policy community is up $7.1 million or eleven% from 2017 yr-conclusion levels. From a profitability standpoint, overseas trade favorable points and a favorable adjustment draw the transition tax out to mitigate the larger labor and fabric charges that impacted their bottom line this yr. They proceed to hang pricing company as they toil through their higher cost stock on end. concerning the tariffs that had been implemented in 2018, they estimate that about 10% of their consolidated annual revenues are at the moment impacted.

    At this element, the bulk of these charges contain been handed along to their customers in the form of invoice can charge. They proceed to monitor the situation carefully as they system the tentative March 1 time limit for the U.S. accomplishing a pretty favorable cope with China in bar nonexistent event extra increases on existing tariffs. typical, they stay cautiously confident with the continued income boom and profitabilities as they enter 2019.

    And with that, i would flip it over to Craig to dash in the course of the fiscal replace.

    Craig Brosious -- vice president of Finance

    Thanks, Dan. To supply a quick recap on income. revenue during the fourth quarter were $142.7 million. through geographic segment, North america earnings contain been $70.3 million, Asia income were $49.1 million and Europe contain been $23.3 million.

    with the aid of product neighborhood, Connectivity solutions income had been $46.four million, Magnetic solutions income were $forty eight.6 million and vigour options and insurance diagram revenue were $47.7 million. grievous profit margin expanded to 21.3% in the fourth quarter of 2018 as in comparison with 18.5% within the fourth quarter of 2017 as incremental earnings in 2018 ended in more suitable fastened can permeate absorption offsetting larger labor expenses bar nonexistent over the yr. moreover, their grievous earnings margin bar nonexistent through the fourth quarter of 2017 contain been impacted through inventory-related costs totaling $2 million in connection with keeping their stock on the lower can permeate or net realizable cost. Their selling, commonplace and administrative expenses were $22.2 million or 15.6% of income as in comparison with $21.1 million or 17.6% of income in the fourth quarter of 2017.

    while the enlarge in SG&A costs bar nonexistent the route through the 2018 length $900,000 pertains to a decline in market price of their COLI policies, which changed into in accordance with the daily inventory market recreation during the fourth quarter of 2018. they now contain already began to peer this transpose in 2019. different offsetting components that affected that the variance in the fourth-quarter durations had been better legal and expert charges of $800,000 offset by using a lessen in unhealthy debt price of $500,000 and a discount in depreciation and amortization of $four hundred,000. On a go-ahead groundwork, they might forecast SG&A to dash between $20 million and $21 million per quarter within the nigh time period, barring any huge fluctuations in foreign currency echange.

    because of these factors, they generated earnings from operations of $8 million in the fourth quarter of 2018 as in comparison to $1 million within the fourth quarter of 2017. pastime expense changed into -- i'm sorry, $1.4 million in the fourth quarter of 2018, down $900,000 from the identical duration closing yr. in case you withhold in mind, they refinanced their credit agreement in the fourth quarter of 2017, which ended in an acceleration of deferred financing cost amortization of $1 million during the remaining year's fourth quarter. Their provision for profits taxes became $2.four million for the fourth quarter of 2018 compared to $19.2 million bar nonexistent through final year's fourth quarter.

    the supply for revenue taxes prerogative through the fourth quarter of 2018 was unfavorably impacted via taxes on international salary, the GILTI tax, partially offset by a reduce within the U.S. tax price from 35% to 21% in 2018. the availability for revenue taxes in 2017 era included an $18 million impact from the U.S. Tax Cuts and Jobs Act, which become enacted on December 22, 2017.

    profits per participate for category a common shares was $0.31 per participate in the fourth quarter of 2018 as compared with a loss of $1.sixty six per participate in the fourth quarter of 2017. earnings per participate for class B common shares was $0.33 per participate within the fourth quarter of 2018 as compared with the lack of $1.seventy four per participate in the fourth quarter of 2017. On a non-GAAP groundwork, which excludes unavoidable peculiar and different nonrecurring items, EPS for category A shares become $0.37 per participate in the fourth quarter of 2018 as compared with the loss of $0.09 per participate in the fourth quarter of 2017. On a non-GAAP groundwork, EPS for class B shares turned into $0.39 per participate in the fourth quarter of 2018 as in comparison with a lack of $0.10 per participate within the fourth quarter of 2017.

    And now i would fancy to proceed through some stability sheet and cash circulation gadgets. Their money and cash equivalents balance at December 31, 2018, changed into $fifty three.9 million, a lessen of $15.4 million from December 31, 2017. prerogative through 2018, they made payments of $9 million towards their wonderful debt steadiness. They likewise used cash for capital charges of $11.6 million, dividend funds of $3.3 million and hobby funds of $four.8 million.

    money owed receivable were $ninety one.9 million at December 31, 2018 as compared with $78.8 million at December 31, 2017. Days income striking contain been 59 days at December 31, 2018, compared to 60 days at December 31, 2017. The boost in debts receivable stability changed into generally because of the bigger revenue volume within the fourth quarter of 2018 as compared to the fourth quarter of 2017. Inventories were $120.1 million at December 31, 2018, up $12.three million from December 31, 2017.

    In January of 2018, they adopted the modern income cognizance regular, which hastens the timing during which they earnings become identified and the corresponding liberate of comprehensive items from their stock balance concerning items held at customer control hubs. except for the results of this adoption, their stock stability would contain elevated by $23.4 million from December 31, 2017, essentially uncooked materials and work-in-growth in keeping with the enhance well-known for their products in 2018. accounts payable had been $fifty six.2 million at December 31, 2018, up $8.2 million from its degree at December 31, 2017 because of the raise in raw material purchases. Bel's total grotesque debt turned into reduced with the aid of $744,000 during the fourth quarter, bringing the balance down to $116 million as of December 31, 2018, aside from deferred financing cost.

    ebook cost per share, which is calculated as stockholders' equity divided by route of their combined A and B classes of daily inventory impressive, become $14.39 per participate at December 31, 2018 as in comparison to $13.13 per participate at December 31, 2017. And now i want to account for the denomination returned to Dan and open the convoke for questions.

    Dan Bernstein -- President and Chief government Officer

    yes. enact they open up the exact questions, please, Allison? 

    Questions and answers:


    actually, sir. [Operator instructions] they are able to now assume their first question from Sean Hannan from Needham & enterprise. please proceed ahead, sir.

    Sean Hannan -- Needham and enterprise -- Analyst

    yes. Thanks. respectable morning, everyone. Dan, i used to breathe looking to descry if I might request you might provide us with a cramped bit of detail across the phase.

    i enact know you offered some on your prepared feedback. can you in bar nonexistent probability acquire into a bit bit extra specificity when it comes to how had been you sentiment with each of these section nowadays and the actions they ramp prerogative here within the first quarter and in '19. and perhaps how that may additionally contain trade or could breathe different versus what you were expecting probably just a brace of months in the past? Any perception there could breathe very effective. Thanks.

    Dan Bernstein -- President and Chief govt Officer

    adequate. Of path, bar nonexistent of their product businesses and bar nonexistent of the subdivisions inside the product corporations, a majority, i would say, 80% of bar nonexistent were very robust. they now contain one community, is the Modular group and the DC to DC neighborhood out of Italy which contain some tremendous clients that they misplaced, but that hasn't been the relaxation to enact with the market conditions simply on account of the situation with these clients. So ordinary everything has been, as you breathe awake of, extraordinarily fine.

    Going into this quarter and subsequent quarter, January become a very -- they saw a tenacious January, and once again, they suppose they enact not descry any alterations within the first quarter. The handiest concerns that they enact contain is there are some IC businesses that are seeing some softening in the market and they enact hear some rumblings that there may breathe too a lot inventory in the pipeline. but to this point it has not affected their revenue or backlog. So again, it's why I respect we're a bit wonderful for the first quarter and for instance, I suppose nigh out after that.

    Sean Hannan -- Needham and company -- Analyst

    adequate. equitable ample. Now as they look into the power neighborhood, it is definitely always a topic on each and every name. there's a all lot that you've done when it comes to correcting the nice concerns from one of the vital acquisitions you've got taken on, there's a remarkable deal you could contain been doing to step-up executions, plenty that you contain executed in incrementally successful modern designs and into modern programs some of which has been getting some momentum.

    and that i suppose you said that a bit bit earlier today. What extra may still they expect within the trajectory of these organizations? Is there the relaxation within the history that's incrementally being labored down or is obtainable a bogey that might speed up the boom trajectory that you're now atmosphere into today? Or how should still they respect about how this continue to enhance as a product section for you? Thanks.

    Dan Bernstein -- President and Chief govt Officer

    good enough. So the vigor community, again, as they brought up over the ultimate two or three years, they trust very strongly that has the best boom expertise for Bel from a accurate-line standpoint. On the power, they did contain is after they acquired the company previous administration truly failed to focus of attention on pleasant and customer service. And it took us a very long time to exchange that; a, first change their manufacturing unit then exchange the client opinion, and over the final 18 months, they now contain bar nonexistent their purchasers are back and believe Bel to breathe a power corporation.

    I feel two issues that they now contain achieved that they now contain changed these days. One became, I consider, as they contain been so desperate for earnings, they took a shotgun approach and really deliver bar nonexistent restrain on their R&D community without getting the character of effects that they would like. So what we've performed is, truly long past from much greater chosen system of what consumers you necessity to deal with, how they suitable into us and should they breathe long-time era shoppers? With that said, they are streamlining their R&D community because they will not contain to proceed with the southbound method, they comprehend what precisely engineers they deserve to lead these products as they circulate ahead. the key difficulty now could breathe that they enact contain two or key key customers that may proceed anywhere from $eight million to $12 million, $13 million.

    And once we're talking about statistics middle-category of customer, they enact contain immense customer classification of valued clientele. again, those fluctuate very immense from a earnings standpoint. once more, however, they enact believe that we've located ourselves much more within the market, and currently I feel they now contain 90 NDA signed on high-effectivity vehicles and we're starting to descry that enterprise proceed from $three million to $5 million. So we're hoping that would double once more, offers us a lot more diversification, and they are working with different information focus classification of customers.

    So they acquire that greater assorted. So again, they are still taking pictures. Their goal has bar nonexistent the time been to acquire vigour to that consistent 10% enlarge over a two to three-12 months period.

    Sean Hannan -- Needham and enterprise -- Analyst

    good enough. that's beneficial. and then closing query prerogative here. just to descry if i will breathe able to acquire some standpoint round a customer of yours without detain or ultimately.

    Huawei, I recall you might breathe now not necessarily even a 5% consumer, but are you able to focus on how enact they play into your enterprise traditionally? And is there the relaxation that they should still respect of thinking about that relationship or income technology and maybe by some means tied to them on a go-forward groundwork? Thanks.

    Dan Bernstein -- President and Chief executive Officer

    neatly, I suppose, again, being a chinese language business, I believe they are inclined to proceed along with chinese providers in China. i know, for instance, they offered their vigor provide neighborhood to Emerson about six years ago, and now former Huawei individuals contain their own vigor give company. So they know it's a troublesome nut to crack. They enact some ICM enterprise, however no longer vast in any respect.

    And for us, it's going to breathe a tenacious edge as a result of they believe people fancy Nortel, Cisco should still prefer up the company that they're losing. So i enact know there are unavoidable nations, Czech Republic, even Canada and the U.S. how they view Huawei going ahead. And that they cannot buy paraphernalia from Huawei for 5G, they will doubtless proceed with -- I failed to signify Nortel, I request for forgiveness, Nokia, that Nokia and Cisco will likely select up that slack and might breathe Alcatel, and these multinational non-chinese language purchasers they enact immense quantity of commerce with them.

    So we're hoping that their commerce should still enlarge as more and more 5G is delivered.

    Sean Hannan -- Needham and company -- Analyst

    Very first rate. Thanks so tons, folks.


    [Operator instructions] And they will now assume a question from Hendi Susanto from G. analysis. please proceed forward.

    Hendi Susanto -- G. analysis -- Analyst

    first rate morning. Dan, you commute to China a remarkable deal. How enact you signify your China market now? How different is it in comparison to a typical 12 months?

    Dan Bernstein -- President and Chief executive Officer

    We at bar nonexistent times -- for us -- bar nonexistent over the realm, I imply, Europe and China there may breathe so a lot uncertainty and how they trust in Donald Trump and the job he's doing. there's giant amount of anxiousness. For us again, for the China market, or not it's always been very complex to demolish into that market as a result of the pricing parameters that you've got promoting to, again, a chinese language consumer. although, a favorable component can breathe 35% of their sales proceed to China, but it surely goes throughout the CEM fancy the Flextronics or Hon Hai, Foxconn, and those are non-chinese groups.

    youngsters, they enact -- they are starting to descry more americans peer at China in a several easy. They recognize the ODMs in Taiwan, they contain majority of their production in China. They at the moment are moving a few of that creation lower back into Taiwan. They descry other multinationals relocating products round to acquire across the tariffs.

    So when you've got production in Malaysia, consume that for bar nonexistent items coming to the States after which you consume your China production to proceed into Europe and the a long route East market. but once again, no one likes uncertainty and that without query with the tariffs there's giant amount of uncertainties and that's not first rate for anyone.

    Hendi Susanto -- G. research -- Analyst

    got it. after which Dan, given solid income growth and your backlog boom in 2018 and existing ERP implementation, how a favorable deal progress in grievous margin and working margin they should expect in 2019?

    Dan Bernstein -- President and Chief executive Officer

    i will depart that to my accounting neighborhood here.

    Craig Brosious -- vice president of Finance

    yes. I respect assuming the within your budget sales enlarge that we're expecting, qualify income increase, I believe they contain some leverage means to movement the grievous margin up to maybe a point, aspect and a half. once more, lots of their construction costs are primarily based in the -- in China and counting on which approach the trade agreements go, it may contain an consequence on the change fees that they should deal with on the can permeate of that -- on the labor costs, exceptionally. So barring any massive moves in these change charges, we've opportunities to extend margins a bit bit.

    Hendi Susanto -- G. research -- Analyst

    after which a further question on charge. So I believe Bel Fuse is coping with enhance in labor charge, and that i suppose that has been there for a long time after which you were mitigating or taking movements or improved your labor charge. after they lag through fancy 2019, when can they examine on an apple-to-apple 12 months-over-12 months assessment in regards to the labor can charge? And fancy how -- and then breathe confident you breathe in a position to quantify how an dreadful lot labor permeate become?

    Craig Brosious -- vice chairman of Finance

    I believe they -- to acquire to an apples-to-apples comparison, they are able to likely should acquire within the third quarter of this year because they had permeate raises going into impact within the first and second quarters of 2018. So I feel as soon as they acquire to the third quarter, they acquire some low cost comparatives.

    Lynn Hutkin -- Director of fiscal Reporting

    The most effectual aspect to add there's, in 2019, we're likewise experiencing elevated labor permeate in Mexico so that you can influence the 2019 length, however changed into not there prerogative through the 2018 period. So they contain that as smartly.

    Hendi Susanto -- G. analysis -- Analyst

    adequate. and then the majority of the tariff cost has been passed to clients. can you quantify how a remarkable deal has been handed and what's next?

    Dan Bernstein -- President and Chief executive Officer

    I respect it's been about $7.eight million, in that latitude.

    Lynn Hutkin -- Director of fiscal Reporting

    In 2018, it become about $2.four million, in total for 2018, in order that become a partial -- that was a partial 12 months.

    Craig Brosious -- vice chairman of Finance

    So fancy Dan had mentioned previously, most of their sales as a minimum coming out of China don't become without detain into the U.S. So we're not enormously impacted through the tariffs. So they contain been capable of -- basically $2.5 million or in order that they needed to add.

    Hendi Susanto -- G. analysis -- Analyst

    good enough. acquired it. thanks.


    [Operator instructions] It appears there aren't any additional questions. Mr. Bernstein, i would fancy to account for the convoke back to you for any additional or closing remarks.

    Dan Bernstein -- President and Chief govt Officer

    thank you for joining us nowadays, and they look to talking to you sooner or later. thanks to your time.


    [Operator signoff]

    length: 29 minutes

    call members:

    Dan Bernstein -- President and Chief government Officer

    Lynn Hutkin -- Director of monetary Reporting

    Craig Brosious -- vp of Finance

    Sean Hannan -- Needham and enterprise -- Analyst

    Hendi Susanto -- G. research -- Analyst

    greater BELFB analysis

    this article is a transcript of this convention convoke produced for The Motley fool. while they try for their fatuous premier, there could breathe mistakes, omissions, or inaccuracies during this transcript. as with bar nonexistent their articles, The Motley fool does not assume any responsibility for your consume of this content material, and they strongly embolden you to enact your personal analysis, together with listening to the convoke yourself and analyzing the business's SEC filings. please descry their phrases and conditions for additional details, together with their mandatory Capitalized Disclaimers of liability.

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    Strongbridge Biopharma plc (SBBP) Q4 2018 Earnings Conference convoke Transcript | true questions and Pass4sure dumps

    Logo of jester cap with thought bubble.

    Image source: The Motley Fool.

    Strongbridge Biopharma plc  (NASDAQ:SBBP)Q4 2018 Earnings Conference CallFeb. 26, 2019, 8:30 a.m. ET

  • Prepared Remarks
  • Questions and Answers
  • Call Participants
  • Prepared Remarks:


    Good morning, ladies and gentlemen, and welcome to the Strongbridge Biopharma Corporate Update and Fourth Quarter 2018 Earnings Conference Call. At this time, bar nonexistent participants are in a listen-only mode. Later they will conduct a question-and-answer session and instructions will result at that time. (Operator Instructions) As a reminder, this convoke will breathe recorded.

    I would now fancy to insert your host for today's conference, Ms. Lindsay Rocco of Elixir Health Public Relations. You now may begin.

    Lindsay Rocco -- Investor Relations

    Thank you and favorable morning, everyone. They are pleased that you could relate us today for Strongbridge Biopharma's fourth quarter and replete year 2018 earnings conference call. Joining me from Strongbridge this morning are Matthew Pauls, President and Chief Executive Officer; Dr. Fred Cohen, Chief Medical Officer; and Brian Davis, Chief pecuniary Officer.

    Before they begin, I would fancy to remind you that during this call, the Company will breathe making forward-looking statements that are theme to risks and uncertainties that may intuition actual results to vary from the results discussed in the forward-looking statements. Reference to these risks and uncertainties are made in today's press release and disclosed in detail in the Company's occasional and current event filings with the U.S. Securities and Exchange Commission.

    In addition, this presentation includes non-GAAP pecuniary measures. This presentation is not intended to breathe a substitute for pecuniary results presented in conformity with generally accepted accounting principles in the U.S. Investors and potential investors are encouraged to review the reconciliation of the pro forma pecuniary measures included in the Company's earnings release. The most directly comparable GAAP information and a reconciliation between the non-GAAP and GAAP figures are included in the Company's fourth quarter 2018 earnings release, which has been furnished on form 8-K.

    I will now turn the convoke over to Matthew Pauls.

    Matthew Pauls -- President and Chief Executive Officer

    Thank you, Lindsay. favorable morning everyone and thanks for joining us. For today's call, I'll commence by providing a brief summary of their fourth quarter and replete year 2018 highlights and results. And then we'll turn the convoke over to Dr. Fred Cohen, their Chief Medical Officer, to debate the ongoing facet III clinical progress program for RECORLEV. Brian Davis, their Chief pecuniary Officer, will then provide a pecuniary overview. They will then open up the convoke for questions.

    With that, let me start by motto that Strongbridge had a tenacious fourth quarter from a clinical, commercial and pecuniary perspective, which is a reflection of their momentum and overall success throughout the past year. As you will hear from the team today, their accomplishments in 2018 demonstrate the value of their rare disease strategy and contain positioned us for future growth as they continue to identify, develop and commercialize considerable treatments for rare diseases. Leveraging the momentum from final year, they entered 2019 with a focus on progressing the progress of RECORLEV for the treatment of endogenous Cushing's syndrome.

    And getting into their most notable fourth quarter accomplishments, let's start with the Novo Nordisk transactions. In December, they significantly strengthened their balance sheet with the sale of the U.S. and Canadian rights of MACRILEN to Novo Nordisk. As previously mentioned, a portion of the upfront cash payment of $145 million from Novo Nordisk to Strongbridge was used to repay bar nonexistent outstanding debt. Other key terms from the transaction comprise that Strongbridge will receive royalties on MACRILEN sales through 2027. And in addition, Novo Nordisk purchased 5.2 million ordinary shares of Strongbridge at a purchase price of $7 per share, resulting in grievous proceeds of $36.7 million.

    Another considerable key strategic term of the transaction is that Novo Nordisk will fund Strongbridge's 23-person rare endocrine commercial bailiwick organization over the next three years to promote MACRILEN in the United States. This aligns with the Company's objective to maximize the potential of MACRILEN, while preparing for the potential regulatory approval of RECORLEV in endogenous Cushing's syndrome, a rare condition that's often treated by the selfsame endocrinologist that diagnose and deal adult growth hormone deficiency.

    Onto their rare neuromuscular franchise. KEVEYIS, their first commercial product, enabled us to build out a rare neuromuscular franchise, which continues to breathe a strategic pillar for the Company. They are committed to serving the needs of the primary occasional paralysis, or PPP community, which is comprised of an estimated 4,000 to 5,000 currently diagnosed patients in the United States. As they prepare for the regulatory filing of potential launch of RECORLEV, there are many parallels and learnings that they contain garnered from the KEVEYIS opportunity that they contain and will continue to leverage across their business.

    Additionally, they believe that the sustain and lore gained from launching KEVEYIS best positioned Strongbridge to acquire the rights to MACRILEN early final year, before selling the rights to Novo Nordisk at the halt of the year. As section of their life cycle management planning for KEVEYIS, they are executing on a number of initiatives with the primary objective of maximizing the value of KEVEYIS over time. They believe that by the halt of 2019 or into early 2020 that they will breathe in a position to provide an update on their life cycle management progress.

    Our investment approach with KEVEYIS focuses on three key areas. Specifically, they are focusing their KEVEYIS commercial investment on, one, utilizing sophisticated data to identify physicians that deal PPP; two, fully leveraging their CareConnection patient services model; and three, engaging the PPP community through both patient advocacy, as well as targeted gregarious media. They peer forward to executing against their 2019 plans and believe that KEVEYIS will generate a positive contribution margin by the halt of the first quarter of 2020.

    So with that I'll turn the convoke over to Dr. Fred Cohen, their Chief Medical Officer, to debate their clinical progress progress for RECORLEV, which they believe continues to contain the potential to breathe a first-line, first-choice therapy for patients with endogenous Cushing's syndrome.

    I will now turn the convoke over to Fred.

    Fredric Cohen -- Chief Medical Officer

    Thank you, Matt. favorable morning, everyone. As previously announced in the third quarter, the pivotal facet III SONICS study of RECORLEV for the treatment of endogenous Cushing's syndrome met its primary endpoint, with urinary free cortisol or UFC confirmed (ph) as daily among 30% of the intent to deal population at the halt of the six-month maintenance phase.

    Detailed initial results from the SONICS study were presented in October at the European NeuroEndocrine Association Annual Meeting, with additional data presented at the European Network for the study of Adrenal Tumors Annual Meeting in November. These analyses illustrated the favorable effects of RECORLEV on hypercortisolism and its comorbidities, particularly sustained improvements in markers of cardiovascular risk, such as LDL-cholesterol, hemoglobin A1C and carcass weight.

    Further SONICS results from the halt of maintenance analyses are planned for presentation at the International Pituitary Congress and the Endocrine Society's Annual Meetings in late March, and at the American Association of Clinical Endocrinology Meeting in April. These results will highlight additional benefits of RECORLEV on the signs and symptoms of hypercortisolism.

    Additionally, submission of a manuscript of the primary efficacy and safety data from SONICS to a peer-reviewed journal is anticipated in the first half of 2019. One-year data from the completed SONICS study are expected to breathe available in the first half of 2019. These data will comprise findings from the six-month extended evaluation phase, which is primarily intended to characterize the long-term safety, tolerability and benefit-risk profile of RECORLEV.

    From a regulatory standpoint, a character C meeting with the FDA is planned within this quarter to seek guidance on the path forward to obtain marketing approval for RECORLEV in the United States, and that process is on track. They anticipate providing an update in the second quarter.

    Finally, the receipt of top line results from the facet III LOGICS study remains on track for the fourth quarter of 2019. As a reminder, LOGICS is a double blind affliction with no planned interim analyses prior to the receipt of these anticipated results.

    And with that, I will now turn the convoke over to Brian Davis for a pecuniary overview.

    A. Brian Davis -- Chief pecuniary Officer

    Thank you, Fred. Their press release contain details of their pecuniary results for the fourth quarter and replete year 2018. Rather than read bar nonexistent of those details, my comments will focus on a few highlights.

    As eminent in the press release, their guidance for KEVEYIS revenues in 2019 is in the $18 million to $20 million range. They contain significantly improved their pecuniary and strategic flexibility as a result of the cash proceeds and anticipated future payments from their transactions with Novo Nordisk, as well as the repayment in replete of their outstanding debt. They ended 2018 with $122.5 million of cash, cash equivalents and no outstanding debt. As for cash runway, they believe the combination of their existing cash resources, anticipated KEVEYIS revenues and payments from Novo Nordisk, as well as the continued prudent management of their operating expenses will provide sufficient capital to support their operations, at least through the first quarter of 2021.

    And Catherine, with that, they are now ready to open up the convoke for questions.

    Questions and Answers:


    (Operator Instructions) And their first question comes from Esther Hong with Janney. Your line is open.

    Esther Hong -- Janney -- Analyst

    Hi, favorable morning. Thanks for taking my questions. So with respect to the character C FDA meeting over RECORLEV, can you provide additional details on your expectations, and then, any potential logistics regarding accelerator approval? And then the second question is, any updates on commerce progress plans in 2019? Thanks.

    Matthew Pauls -- President and Chief Executive Officer

    So Esther, this is Matt. Thank you for the questions. Let me assume them in transpose order. With respect to commerce development, they obviously don't comment on any commerce development-related projects that they may breathe working on. I enact believe that their history here at Strongbridge -- as they continue to build the Company is that they are lively in looking at opportunities and that continues. And that's bar nonexistent I'll jabber on that front. I will contain Dr. Cohen comment on the character C regulatory process and timing.

    Fredric Cohen -- Chief Medical Officer

    Sure. So as I've just -- they enact diagram to contain the discussion with the FDA in the first quarter of this year, and then following digestion of that and then any clarifying dialog they necessity to contain with the FDA, they diagram to update investors by the second quarter with the path forward, as they said. In terms of their foundation case, just to reiterate, they are anticipating that the FDA will lead us toward the necessity for both the replete SONICS as well as the replete LOGICS study for being in hand and included within NDA. Again, that's the foundation case. The upside case for us that they believe is supported with the unmet medical need, the route that SONICS was designed in terms of using a surrogate endpoint that's been established, and the precedent within this division of allowing approval on the basis of the lone open label study, they believe that there is an upside case where there could breathe an accelerated pathway toward the filing, where they foundation it primarily just on the SONICS, to your point around accelerator approval. Again, they enact believe that the dialog that we're anticipating with the FDA in this quarter will create that pathway pellucid for us and then we'll update you guys accordingly.

    And with respect to timing, that's just so -- in the expedited or accelerated upside case, clearly they would breathe working hard to acquire it -- acquire the NDA filed as quickly as possible, probably realistically why they would adore to contain it filed by the halt of the year, at the halt of 2019, it probably would breathe more fancy an early 2020-ish. More details to forward on that, obviously, as they contain more clarity. In the foundation case, it would breathe about a year later than that. I hope that helps.

    Esther Hong -- Janney -- Analyst

    It does. Great, thank you.

    Fredric Cohen -- Chief Medical Officer

    You are welcome.


    Thank you. And their next question comes from Annabel Samimy with Stifel. Your line is open.

    Nick Rubino -- Stifel -- Analyst

    Good morning, everyone. This is Nick Rubino on for Annabel Samimy. Thanks for taking their question. First, how the efforts to educate physicians on titration helped patient retention. Are you still seeing attrition due to the side effects and how enact you descry those dynamics playing out 2019 and beyond? And then second with the one-year SONICS, you had mentioned the safety pieces, but are they getting efficacy measures as well? And then, if I can just sneak in a quick rapidly one, with the MACRILEN revenue numbers you reported this quarter, are those purely royalty revenues or did those comprise replete sales from October and November? Thanks.

    Matthew Pauls -- President and Chief Executive Officer

    Thanks for those questions, Nick. Let me give you a cramped insight on the first question regarding KEVEYIS. They erudite a lot on the KEVEYIS fronts in 2018 regarding both KEVEYIS as well as primary occasional paralysis. And one of the key learnings which you well said was around the need, often to proceed a cramped bit lower and a cramped bit slower in the titration period. And, I'll request Dr. Cohen just to comment briefly on that. I think, they contain some learnings from facet III affliction and then from the clinical -- not just clinical instant -- in the clinical trial, but likewise in the commercial consume too. So, Fred, enact you want to comment on that?

    Fredric Cohen -- Chief Medical Officer

    Yeah. Yeah, sure. Great. So one of the things that they erudite was that there are a significant minority of patients who experienced adverse reactions from the drug early on in the therapy. And one of them -- one of those reactions that's common is on -- a confusion on mental fog, if you will, that occurs. It's a ephemeral response to the drug until the brain can sort of equilibrate and become used to the drug. But when it occurs, it needs to breathe addressed, it needs to breathe managed, and the best route that they know how to manage it is by lowering the dose of the drug.

    Well, it took us a while, I think, number one, to recognize that this was a reaction that was responsible for some patients discontinuing from the drug. And once they did recognize that, they deliver in status a string of educational efforts aimed at physicians initially and then later direct-to-patient education and trust through the consume of, for example, patient ambassadors that contain given their time generously to succor educate other patients. And so we're making remarkable progress. I think, it's equitable to jabber we've seen already changes in the route the titrations are going. And we've gotten feedback from patients who are now able to overcome the initial side-effects and contain stayed on the drug, because they are seeing benefits from it in many cases. So, I hope that addresses that section of that question.

    Nick Rubino -- Stifel -- Analyst

    Yes, that's great. Then, with regards to the --

    Matthew Pauls -- President and Chief Executive Officer

    Yes, the MACRILEN revenues during the fourth quarter were product sales by Strongbridge. There were no royalties in their revenues for the quarter.

    Fredric Cohen -- Chief Medical Officer

    Yes, there was likewise a question you had about the 1-year RECORLEV data. So on the top line data that they will breathe sharing with you will comprise primarily safety data. But likewise they did measure some efficacy data as well, including urine free cortisol, as well as those comorbidity markers. And I'm pretty confident we'll breathe sharing that with you at the time they release the top line results.

    Nick Rubino -- Stifel -- Analyst

    Alright. Great. Thank you guys.

    Matthew Pauls -- President and Chief Executive Officer

    Yes, thanks for the questions.


    Thank you. And their next question comes from Hartaj Singh with Oppenheimer & Company. Your line is open.

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Great, thanks. Thanks for the question and a favorable year. Just a brace of questions, Matt I've got. On your interactions with the FDA prior to this meeting, I assume you might contain already submitted a sort of a briefing package and kindly of there contain been some interactions back and forth. Can you just give some color on, sort of, the gist of those interactions and what are some of the questions that maybe you're asking or FDA is wanting to breathe addressed prior to the actual meeting? And then a second question, just on KEVEYIS, to result up with the previous question. Matt, can you just give some color on, sort of, modern patients, continuing patients, what sort of -- how many patients are staying on drug, on average, just any color around what that dynamic is, because it seems that the drug is growing quarter-on-quarter. And then just your thoughts about that going forward. And then just a quick housekeeping question after that. Thank you.

    Matthew Pauls -- President and Chief Executive Officer

    Great, thank you Hartaj. So on the regulatory question related to RECORLEV. As a standard course for us, they don't comment on the interactions prior to having their final interpretation of the dialog. So more to forward in the second quarter. And I think, Fred articulated well earlier what their foundation case assumptions are meeting both trials and the upside case around an accelerated potential approval, given the significant unmet necessity in Cushing syndrome, UFC being a stated accepted surrogate endpoint by the FDA, resoundingly positive, and they believe compelling SONICS data. And then, in this division, in the review of Cushing's syndrome, lone affliction approvals. So that's where we're at and we'll provide an update in the second quarter.

    And then with respect to KEVEYIS -- and your question on KEVEYIS. So what they know is that there -- they are confident there are 4,000 to 5,000 patients currently diagnosed with PPP. They are seeing modern patients regularly forward onto KEVEYIS. And they are doing a much better job, as Fred mentioned, with respect to patient-to-patient interaction, patient-to-physician interaction, recommendations around maybe lower and slower titration or down titration. So they are seeing patients more often than not -- now stay on the drug through that kindly of an interim period.

    And so, the immense focus for us here is being smart and choiceful about their investment plane with respect to KEVEYIS, because it's considerable for many reasons to try to drive KEVEYIS to profitability on a stand-alone basis as quickly as possible. And we're confident that we're on that path by the halt of the first quarter of 2020. And parallel to that, given the fact that there are no other drugs really that are in progress for the treatment of this ultra-rare genetic neuromuscular condition, PPP, they are working very feverishly and hard, as we've said previously, around life cycle management opportunities. They would adore to contain the opportunity to contain more runway with KEVEYIS. So more to forward by the -- probably by the halt of the year, again, maybe into 2020 on their life cycle management plans. But this is a market that prior to us relaunching the drug really had no investment ever, was disorganized, unstructured. And we're confident that we're on the path to structuring it, organizing it and getting KEVEYIS to profitability, so that we're being smart and choiceful and prudent with respect to their investment.

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Great. And Matt, that's remarkable color. Just a follow-up on that. So roughly speaking, are you sort of seeing patients that are coming that are modern to KEVEYIS being equal to patients dropping off, or is there less of a drop-off, just what's the dynamic there between the modern and the continuing patients and the patients that are leaving, whether it's titration or for other issues?

    Matthew Pauls -- President and Chief Executive Officer

    So, they -- the trend is that more patients are staying on the drug than off. And that's based on the interventions, really in -- I guess in the back half of the third quarter and the fourth quarter by us, and of course to-date. So what we're -- the patient identification and identifying patients who are very motivated and physicians that are motivated and then providing the very tenacious plane of support and service for them through that process, given the potency of KEVEYIS. I signify the drug really works. It really works. They are having success getting patients through that short -- I don't know -- for a four-to-six-week period-ish, that range. But it's upwards of eight weeks.

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Got it. And then just one housekeeping question on -- just how to believe about operating expenditures, sort of, going forward for the year, just any thoughts there? And again, thank you so very much.

    Matthew Pauls -- President and Chief Executive Officer

    Yes, Hartaj. This is Brian, Hartaj. Thanks for that. So, on the cash basis, as I mentioned, we're looking at a runway that takes us through the first quarter of 2021. I believe they contain the benefit of the Novo Nordisk subsidy coming online here in 2019 to offset the commercial application around MACRILEN. And so we'll contain a cramped transition working through Q1 to acquire down on a cash scorch basis. But they feel pretty comfortable in that low-to-mid teens zone as they lag forward. In fact, if you assume that $122 million cash balance and just by simple averaging over the subsequent nine quarters through the first quarter of 2021 that comes up to about $13.5 million. So a cramped more in this year, reflecting the transition down, reflecting we've got some increased RECORLEV program expenses (inaudible) tall water mark, if you will, for the RECORLEV program, because they contain SONICS and LOGICS and OPTICS running simultaneously, but obviously SONICS expense is winding down now that the one-year data will breathe coming through. So again, enough cash to acquire us at least through the first quarter. And obviously, we'll contain more definition on that as they proceed along as to how much more at least it can be.

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Great. And I really treasure it. Thank you very much.


    Thank you. And their next question comes from Liisa Bayko with JMP Securities. Your line is open.

    Liisa Bayko -- JMP Securities -- Analyst

    Hi, congratulations on the quarter. Just a brace of questions for me, mainly about KEVEYIS. So first of all, I want to jabber congratulations, I signify you've made this into a product that reached $20 million this year, which is certainly a lot higher than where you thought the product brace of years ago. They technically were only talking about $1 million. So it's obvious that you've done a tremendous job in creating this market. But again (ph) your guidance a cramped bit, for this year, looks fancy $4.4 million is the kindly of what you're coming off 4Q (ph). Your guidance of $18 million to $20 million implies a cramped bit of slowing growth. So is that -- are patients adds still happening at the selfsame rate or is that lower, are you having -- struggling to find more patients or is it based on -- basically from your comments, I'm thinking maybe less revenue per patient because of dose titration. What's the kindly of dynamic with add indications or revenue per patient? How does that -- what's sort of underlying the guidance?

    A. Brian Davis -- Chief pecuniary Officer

    Yes, this is Brian. So again, we're continuing the favorable news, is find patients. And they feel really favorable about the bailiwick compel they contain in status and they're performing very strongly, as Matt indicated in his comments and in the prior answer. We've had a lot of learning in this market and working through how best not only to attract patients, but likewise to retain patients. So they were conscious of the revenue range that they deliver out there, $18 million to $20 million and where we've forward off of this year, we're going to breathe conservative in their approach, But the patient retention piece takes time and they believe we're working through it.

    On the expense side, they contain focused their investment and made decisions to reduce the territories to succor create confident they acquire to a positive contribution margin or a profitability standpoint for the product. They went from 21 down to 17 territories. They focused their marketing expenses to those -- really targeted toward the patient, in order to succor bar nonexistent of the revenue expenses to line up. So, we'll withhold working through it, but they feel favorable about their skill to not only hit this range, but likewise to acquire this product to breathe one that's a profitable one. And as you pointed out at the beginning, it was a very challenging market to enter into. You're quite correct. Before they had acquired the drugs -- the drug, I should say, its sales had been less than $1 million in a year. So, yes.

    Matthew Pauls -- President and Chief Executive Officer

    Yes, so Liisa, the other piece on that to note is, as I mentioned, in parallel, they are looking at life cycle management opportunities and we'll update the market probably by the halt of the year or in early 2020. And if there are potential opportunities to extend the life and runway of KEVEYIS, they will obviously, probably revisit their investment strategy with respect to the brand. But prerogative now, it is to acquire it to profitability as quickly as practicable and to grow the top line, which they will enact both. And exiting the year, the low halt of the range, we're tracking already to the low halt of the range. So hopefully, there will breathe some -- even more enhanced or increased momentum as they proceed the year.

    Liisa Bayko -- JMP Securities -- Analyst

    Okay, equitable enough. And then, I guess, as you peer longer-term, are you still thinking this product is kindly of easily a brace hundred million or enact you contain some other kindly of target in intuition longer-term now that you've had more sustain selling the drug? Just thinking about how, kindly of, directionally where they should breathe headed in terms of modeling. Thanks.

    A. Brian Davis -- Chief pecuniary Officer

    I believe -- this is Brian. I think, there's a brace of things there, Liisa, that really play into that. So one is the patient penetration. So they believe we've got an opportunity and we're really just at the genesis stages of it in terms of patient penetration. Now Matt and Fred were taking a cramped bit earlier about life cycle management opportunities, having a longer commercial runway will certainly allow us the opportunity to compass peak sales levels over a longer era of time that they contain (inaudible). We're just operating with the current regulatory exclusivity. I think, the other piece that obviously plays into in this environment is around the price of the drug. And I would note, they continue to breathe very cautious in their thinking around that. So we'll talk about pricing strategy, specifically, but we're very awake of the environment that we're in and we're going to act appropriately in that environment, and really try to enact bar nonexistent they can to create confident patients -- as many patients contain access to the drug as practicable over time. But they believe there's a longer runway in terms of reaching out to patients and life cycle management opportunities would certainly succor to acquire us up to higher peak sales levels.

    Liisa Bayko -- JMP Securities -- Analyst

    Okay. Thank you very much for your comments. treasure it.

    A. Brian Davis -- Chief pecuniary Officer

    Thanks Liisa.


    Thank you. And I'm showing no further questions at this time. I'd fancy to turn the convoke back to Mr. Matthew Pauls for any closing remarks.

    Matthew Pauls -- President and Chief Executive Officer

    Thank you. In summary, these fourth quarter and replete year 2018 results underscore that their strategy, their assets, their people, their capital and their infrastructure well position us for continued success in 2019 and beyond. Thank you for joining today's convoke and for your continued support.


    Ladies and gentlemen, thank you for participating in today's conference. This does conclude today's program. You may bar nonexistent disconnect. Everyone contain a remarkable day.

    Duration: 33 minutes

    Call participants:

    Lindsay Rocco -- Investor Relations

    Matthew Pauls -- President and Chief Executive Officer

    Fredric Cohen -- Chief Medical Officer

    A. Brian Davis -- Chief pecuniary Officer

    Esther Hong -- Janney -- Analyst

    Nick Rubino -- Stifel -- Analyst

    Hartaj Singh -- Oppenheimer & Company -- Analyst

    Liisa Bayko -- JMP Securities -- Analyst

    More SBBP analysis

    Transcript powered by AlphaStreet

    This article is a transcript of this conference convoke produced for The Motley Fool. While they strive for their fatuous Best, there may breathe errors, omissions, or inaccuracies in this transcript. As with bar nonexistent their articles, The Motley Fool does not assume any responsibility for your consume of this content, and they strongly embolden you to enact your own research, including listening to the convoke yourself and reading the company's SEC filings. please descry their Terms and Conditions for additional details, including their Obligatory Capitalized Disclaimers of Liability.

    Motley Fool Transcribers has no position in any of the stocks mentioned. The Motley Fool has no position in any of the stocks mentioned. The Motley Fool has a disclosure policy.

    Nektar Therapeutics to Webcast Conference convoke for Analysts and Investors at the 2019 ASCO-SITC Clinical Immuno-Oncology Symposium | true questions and Pass4sure dumps

    SAN FRANCISCO, Feb. 25, 2019 /PRNewswire/ -- Nektar Therapeutics (NKTR) announced today that it will webcast an analyst and investor conference convoke with lead investigator of the REVEAL study, Dr. Adi Diab, and company management on Friday, March 1, 2019 at 3:00 p.m. Pacific Time during the 2019 ASCO-SITC Clinical Immuno-Oncology Symposium. The event will result Friday's oral presentation by Dr. Diab of preliminary data from the ongoing dose-escalation stage of the disclose facet 1/2 clinical study evaluating the combination of TLR agonist, NKTR-262, with a CD122-preferential IL-2 pathway agonist, bempegaldesleukin* (NKTR-214), in patients with locally advanced or metastatic solid tumors.

    Details on the Analyst Call:

    Date and Time: Friday, March 1, 2019 at 3:00 p.m. Pacific Time

    Dial-in: 877-881-2183 (toll-free) or 970-315-0453 (international)

    Passcode: 6970019

    The conference convoke will include lead investigator on the disclose study, Dr. Adi Diab, coadjutant Professor of Melanoma Medical Oncology at The University of Texas MD Anderson Cancer Center. The webcast and slides for the conference convoke can breathe accessed through a link that is posted on the Investors section of the Nektar website at The event will likewise breathe available for replay for two weeks on the company's website,

    Details on the Oral Presentation at ASCO-SITC:

    Abstract Title: "Phase Ib: preliminary clinical activity and immune activation for NKTR-262 [TLR 7/8 

    agonist] plus NKTR-214 [CD122-biased agonist] in patients (pts) with locally advanced or metastatic solid

    tumors (REVEAL facet Ib/II Trial)"

    Abstract: #28

    Presenter: Dr. Adi Diab, MD Anderson Cancer Center

    Session: Oral Abstract Session B

    Date and Time: Friday, March 1, 2019, 1:00 p.m.-2:15 p.m. Pacific Time

    About NektarNektar Therapeutics is a research-based, progress stage biopharmaceutical company whose mission is to ascertain and develop innovative medicines to address the unmet medical needs of patients. Their R&D pipeline of modern investigational medicines includes treatments for cancer, auto-immune disease and habitual pain. They leverage Nektar's proprietary and proven chemistry platform in the discovery and design of their modern therapeutic candidates. Nektar is headquartered in San Francisco, California, with additional operations in Huntsville, Alabama and Hyderabad, India. Further information about the company and its drug progress programs and capabilities may breathe create online at

    * rINN (recommended International Nonproprietary Name)


    View original content:

    American Outdoor Brands Corporation® Third Quarter Fiscal 2019 pecuniary Release and Conference convoke Alert | true questions and Pass4sure dumps

    SPRINGFIELD, Mass., Feb. 22, 2019 /PRNewswire/ -- American Outdoor Brands Corporation (nasdaq global select:AOBC) today announced that it plans to release its third quarter fiscal 2019 pecuniary results on Thursday, March 7, 2019, after the nigh of the market. The replete text of the press release will breathe available on the American Outdoor Brands web site at under the Investor Relations section.

    The company will host a conference convoke and webcast on March 7, 2019, to debate its third quarter fiscal 2019 pecuniary and operational results. Speakers on the conference convoke will comprise James Debney, President and Chief Executive Officer, and Jeffrey D. Buchanan, Executive Vice President and Chief pecuniary Officer. The conference convoke may comprise forward-looking statements. The conference convoke and webcast will commence at 5:00 p.m. Eastern Time (2:00 p.m. Pacific Time). Those interested in listening to the conference convoke via telephone may convoke directly at (844) 309-6568 and reference conference identification number 9683518. No RSVP is necessary. The conference convoke audio webcast can likewise breathe accessed live and for replay on the company's website at, under the Investor Relations section. The company will maintain an audio replay of this conference convoke on its website for a era of time after the call. No other audio replay will breathe available.

    About American Outdoor Brands Corporation American Outdoor Brands Corporation (nasdaq global select:AOBC) is a provider of trait products for shooting, hunting, and rugged outdoor enthusiasts in the global consumer and professional markets. The Company reports two segments: Firearms and Outdoor Products & Accessories. Firearms manufactures handgun long gun, and suppressor products sold under the Smith & Wesson®, M&P®, Thompson/Center Arms™, and Gemtech® brands, as well as provides forging, machining, and precision plastic injection molding services. AOB Outdoor Products & Accessories is the industry leading provider of shooting, reloading, gunsmithing, gun cleaning supplies, specialty tools and cutlery, and electro-optics products and technology for firearms. They produce innovative, top trait products under the brands Caldwell®; Wheeler®; Tipton®; Frankford Arsenal®; Lockdown®; BOG®; Hooyman®; Smith & Wesson® Accessories; M&P® Accessories; Thompson/Center Arms™ Accessories; Schrade®; ancient Timer®; Uncle Henry®; Imperial®; BUBBA®; UST®;  Lasergrips®, Laserguard®, LiNQ®, Lightguard®, Defender Series™, Rail Master®, and LaserLyte.  For more information on American Outdoor Brands Corporation, convoke (844) 363-5386 or log on to  

    Contacts:Liz Sharp, VP Investor RelationsAmerican Outdoor Brands Corporation(413)

    View original content to download multimedia:

    SOURCE American Outdoor Brands Corporation

    Copyright (C) 2019 PR Newswire. bar nonexistent rights reserved

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